Photothermally Controlled Methotrexate Release System Using β-Cyclodextrin and Gold Nanoparticles

Photothermally Controlled Methotrexate Release System Using β-Cyclodextrin and Gold Nanoparticles

The inclusion compound (IC) of cyclodextrin (CD) containing the antitumor drug Methotrexate (MTX) as a guest molecule was obtained to increase the solubility of MTX and decrease its inherent toxic effects in nonspecific cells. The IC was conjugated with gold nanoparticles (AuNPs), obtained by a chem...

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Bibliographic Details
Main Authors: Nataly Silva, Ana Riveros, Nicolás Yutronic, Erika Lang, Boris Chornik, Simón Guerrero, Josep Samitier, Paul Jara, Marcelo J. Kogan
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Nanomaterials
Subjects:
inclusion compound
cyclodextrin
Methotrexate
delivery system
gold nanoparticles
photothermal release
laser
irradiation
Online Access:https://www.mdpi.com/2079-4991/8/12/985

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