Downregulated lncRNA RCPCD promotes differentiation of embryonic stem cells into cardiac pacemaker-like cells by suppressing HCN4 promoter methylation
Abstract Long non-coding RNA (lncRNA) is receiving increasing attention in embryonic stem cells (ESCs) research. However, the roles of lncRNA in the differentiation of ESCs into pacemaker-like cells are still unclear. Therefore, the present study aims to explore the roles and mechanisms of lncRNA in...
Main Authors: | Ye Zhu, Jia You, Wei Wei, Jianjun Gu, Chao Xu, Xiang Gu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-03949-5 |
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