Reduced Dynamic Coupling Between Spontaneous BOLD-CBF Fluctuations in Older Adults: A Dual-Echo pCASL Study

Measurement of the dynamic coupling between spontaneous Blood Oxygenation Level Dependent (BOLD) and cerebral blood flow (CBF) fluctuations has been recently proposed as a method to probe resting-state brain physiology. Here we investigated how the dynamic BOLD-CBF coupling during resting-state is a...

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Bibliographic Details
Main Authors: Piero Chiacchiaretta, Francesco Cerritelli, Giovanna Bubbico, Mauro Gianni Perrucci, Antonio Ferretti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00115/full