Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer

Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer

Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-displayed libraries in mammalian model systems, usi...

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Bibliographic Details
Main Authors:	James W. Gillespie, Liping Yang, Laura Maria De Plano, Murray A. Stackhouse, Valery A. Petrenko
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Viruses
Subjects:	phage display in vivo landscape phage directed molecular evolution breast cancer tissue-selective motifs short linear motifs (slims) elementary binding units (ebus)
Online Access:	https://www.mdpi.com/1999-4915/11/11/988

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