CASPASE-3 and CASPASE-8 activity in right ventricular myocardial cells in experimental arterial hypertension

CASPASE-3 and CASPASE-8 activity in right ventricular myocardial cells in experimental arterial hypertension

Caspase-3 and caspase-8 activity in right ventricular myocardial cells of rabbits with experimental arterial hypertension (AH) was investigated. Caspase-3 activity significantly increased at 2 and 4 weeks after modeling of AH. Obtained data demonstrated increased apoptosis in right ventricular myoca...

Full description

Bibliographic Details
Main Authors: M M Azova, M L Blagonravov, V A Frolov
Format: Article
Language:English
Published: Peoples’ Friendship University of Russia (RUDN University) 2011-12-01
Series:RUDN Journal of Medicine
Subjects:
апоптоз
каспаза
миокард
артериальная гипертензия
Online Access:http://journals.rudn.ru/medicine/article/view/3559
Description
Summary:Caspase-3 and caspase-8 activity in right ventricular myocardial cells of rabbits with experimental arterial hypertension (AH) was investigated. Caspase-3 activity significantly increased at 2 and 4 weeks after modeling of AH. Obtained data demonstrated increased apoptosis in right ventricular myocardial cells in experimental arterial hypertension. Absence of significant increasing of caspase-8 activity indicates the predominance of intrinsic apoptogenic signals.
ISSN:2313-0245
2313-0261

Similar Items