A Near-infrared Benzothiazole-based Chemodosimeter for Rapid and Selective Detection of Hydrogen Sulfide

• Main Author: Safacan KOLEMEN
• Format: Article
• Language: English
• Published: Turkish Chemical Society 2021-05-01
• Series: Journal of the Turkish Chemical Society, Section A: Chemistry
• Subjects: fluorescence; hydrogen sulfide; benzothiazole; near-infrared imaging; chemodosimeters
• Online Access: https://dergipark.org.tr/tr/pub/jotcsa/issue/60129/853370

Hydrogen sulfide (H2S) is a biologically relevant gaseous molecule, which involves in a wide variety of physiological and pathological processes. Thus, detection of H2S is highly valuable in order to clarify its complex roles. In this study, a new benzothiazole-based donor-acceptor type H2S selective chemodosimeter (HP-1) was synthesized and its H2S detection capabilities were investigated in aqueous solutions. HP-1 exhibited a red-shifted absorption signal at 530 nm and a near-infrared (NIR) fluorescence peak at 680 nm as a result of enhanced intramolecular charge transfer (ICT) in the presence of H2S, which enabled a selective and very rapid ratiometric fluorescent detection. HP-1 was also showed to be highly sensitive toward H2S with a very low limit of detection value.