Synthesis, Characterization and Antioxidant Activity of Rutin Complexes

• Main Authors: Qadeer K. Panhwar, Shahabuddin Memon
• Format: Article
• Language: English
• Published: National Centre of Excellence in Analytical Chemsitry 2014-12-01
• Series: Pakistan Journal of Analytical & Environmental Chemistry
• Online Access: http://www.ceacsu.edu.pk/PDF%20file/Volume%2015%20No%202/60-70-PJAEC-25082014-05-Ok.pdf

Rutin, one of the excellent chelating agents, has been made to react with Zr4+ and MoO42- ions to get metal complexes in methanol. The synthesis, spectral properties (UV-Vis, 1H NMR, 13C NMR, IR), thermal behavior and antioxidant activity of these complexes have been studied. It has been observed that rutin forms deep yellow colored complexes of mononuclear composition (through 5OH-4CO system in case of Zr4+/catechol site in case of MoO42-) having stoichiometry, 1:2 and 1:1 for Zr4+ and MoO42- ions, respectively. It has been further noticed that these complexes are formed at different pHs, i.e. 4.0 and 8.0 pHs suitable for Zr4+ and MoO42- complexes, respectively. Thermograms also confirm the results of IR and support the presence of water molecules in complexes. Relative antioxidant activity of the rutin ligand, zirconium-rutin and molybdenum-rutin complexes was determined. It was found that both metal complexes have higher antioxidant activity than rutin alone.