The interdependence of excitation and inhibition for the control of dynamic breathing rhythms
Excitatory neurons in the preBötzinger Complex generate bursting activity responsible for breathing, but these alone cannot generate physiological breathing frequencies. Here the authors show how inhibition regulates refractory properties of excitatory neurons to allow dynamic breathing rhythms.
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-03223-x |
Summary: | Excitatory neurons in the preBötzinger Complex generate bursting activity responsible for breathing, but these alone cannot generate physiological breathing frequencies. Here the authors show how inhibition regulates refractory properties of excitatory neurons to allow dynamic breathing rhythms. |
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ISSN: | 2041-1723 |