Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients

Background: Apelin is a potent endogenous inotropic peptide with a major role in counteracting the aldosterone and angiotensin II and their negative effects on the cardiovascular system. The exact role of apelin in the patho-physiology of this disease is not well understood. We aimed to investigate...

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Main Authors: Goidescu Cerasela Mihaela, Anton Florin Petru, Leucuța Daniel Corneliu, Mircea Petru Adrian, Vida-Simiti Luminița Animarie
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
Online Access:https://doi.org/10.1515/rrlm-2016-0035
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spelling doaj-ea6d308eeb694ce5a108b9f1188037b02021-09-05T14:00:22ZengSciendoRomanian Journal of Laboratory Medicine2284-56232016-12-0124439941210.1515/rrlm-2016-0035Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patientsGoidescu Cerasela Mihaela0Anton Florin Petru1Leucuța Daniel Corneliu2Mircea Petru Adrian3Vida-Simiti Luminița Animarie4Department of Internal Medicine, Cardiology and Gastroenterology, 1st Medical Clinic, UMF ‟Iuliu Hațieganu” Cluj-Napoca, RomaniaDepartment of Internal Medicine, Cardiology and Gastroenterology, 1st Medical Clinic, UMF ‟Iuliu Hațieganu” Cluj-Napoca, RomaniaMedical Informatics and Biostatistics Department, UMF ‟Iuliu Hațieganu” Cluj-Napoca, RomaniaDepartment of Internal Medicine, Cardiology and Gastroenterology, 1st Medical Clinic, UMF ‟Iuliu Hațieganu” Cluj-Napoca, RomaniaDepartment of Internal Medicine, Cardiology and Gastroenterology, 1st Medical Clinic, UMF ‟Iuliu Hațieganu” Cluj-Napoca, RomaniaBackground: Apelin is a potent endogenous inotropic peptide with a major role in counteracting the aldosterone and angiotensin II and their negative effects on the cardiovascular system. The exact role of apelin in the patho-physiology of this disease is not well understood. We aimed to investigate the possible associations of apelin-13 with clinical and paraclinical characteristics in HF patients as well as studying its dynamics during the course of the heart failure.https://doi.org/10.1515/rrlm-2016-0035heart failureapelinnt-probnppeptide
collection DOAJ
language English
format Article
sources DOAJ
author Goidescu Cerasela Mihaela
Anton Florin Petru
Leucuța Daniel Corneliu
Mircea Petru Adrian
Vida-Simiti Luminița Animarie
spellingShingle Goidescu Cerasela Mihaela
Anton Florin Petru
Leucuța Daniel Corneliu
Mircea Petru Adrian
Vida-Simiti Luminița Animarie
Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
Romanian Journal of Laboratory Medicine
heart failure
apelin
nt-probnp
peptide
author_facet Goidescu Cerasela Mihaela
Anton Florin Petru
Leucuța Daniel Corneliu
Mircea Petru Adrian
Vida-Simiti Luminița Animarie
author_sort Goidescu Cerasela Mihaela
title Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
title_short Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
title_full Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
title_fullStr Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
title_full_unstemmed Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
title_sort serum level of apelin-13 negatively correlated with nt-probnp in heart failure patients
publisher Sciendo
series Romanian Journal of Laboratory Medicine
issn 2284-5623
publishDate 2016-12-01
description Background: Apelin is a potent endogenous inotropic peptide with a major role in counteracting the aldosterone and angiotensin II and their negative effects on the cardiovascular system. The exact role of apelin in the patho-physiology of this disease is not well understood. We aimed to investigate the possible associations of apelin-13 with clinical and paraclinical characteristics in HF patients as well as studying its dynamics during the course of the heart failure.
topic heart failure
apelin
nt-probnp
peptide
url https://doi.org/10.1515/rrlm-2016-0035
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AT leucutadanielcorneliu serumlevelofapelin13negativelycorrelatedwithntprobnpinheartfailurepatients
AT mirceapetruadrian serumlevelofapelin13negativelycorrelatedwithntprobnpinheartfailurepatients
AT vidasimitiluminitaanimarie serumlevelofapelin13negativelycorrelatedwithntprobnpinheartfailurepatients
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