Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?

Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?

The antitumor effect of bisphosphonates (BPs) is under increasing scrutiny. Preclinical and clinical evidence has shown that BPs might sensitize breast tumors to chemotherapy. Here, we present a review of current preclinical and clinical evidence for antitumor effects of BPs, and evaluate how BPs mi...

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Bibliographic Details
Main Authors: Ayoub Charehbili, Duveken B. Y. Fontein, Judith R. Kroep, Gerrit-Jan Liefers, Johannes W. R. Nortier, Cornelis J. H. van de Velde
Format: Article
Language:English
Published: MDPI AG 2013-10-01
Series:Journal of Clinical Medicine
Subjects:
bisphosphonates
zoledronic acid
chemotherapy
neoadjuvant
postmenopausal
Online Access:http://www.mdpi.com/2077-0383/2/4/188

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