From Squid to Mammals with the HH Model through the Nav Channels' Half-Activation-Voltage Parameter.

The model family analyzed in this work stems from the classical Hodgkin-Huxley model (HHM). for a single-compartment (space-clamp) and continuous variation of the voltage-gated sodium channels (Nav) half-activation-voltage parameter ΔV1/2, which controls the window of sodium-influx currents. Unlike...

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Bibliographic Details
Main Authors: Nedialko I Krouchev, Frank Rattay, Mohamad Sawan, Alain Vinet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667926?pdf=render