PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels

PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels

<p>Abstract</p> <p>Objective</p> <p>Atherosclerosis is a chronic inflammatory process. Poly(ADP-ribose) polymerase-1 (PARP), a nuclear enzyme linked to DNA repair, has been shown to be involved in atherogenesis; however, the effects on dendritic cells, T cells and serum...

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Bibliographic Details
Main Authors: Erbel C, Achenbach J, Akhavanpoor M, Dengler TJ, Lasitschka F, Gleissner CA, Bea F, Katus HA, Szabo G
Format: Article
Language:English
Published: BMC 2011-08-01
Series:European Journal of Medical Research
Subjects:
PARP
atherosclerosis
inflammation
oxLDL
dendritic cells
T cells
Online Access:http://www.eurjmedres.com/content/16/8/367

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