Impact of Somatic Mutations in Non-Small-Cell Lung Cancer: A Retrospective Study of a Chinese Cohort

Impact of Somatic Mutations in Non-Small-Cell Lung Cancer: A Retrospective Study of a Chinese Cohort

Hai-bo Shen1 ,* Jie Li1 ,* Yuan-shan Yao,1 Zhen-hua Yang,1 Yin-jie Zhou,1 Wei Chen,2 Tian-jun Hu1 1Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang 315010, People’s Republic of China; 2Zhongyuan Union Clinical Laboratory Co., Ltd, Tianjin, People’s Re...

Full description

Bibliographic Details
Main Authors:	Shen H, Li J, Yao Y, Yang Z, Zhou Y, Chen W, Hu T
Format:	Article
Language:	English
Published:	Dove Medical Press 2020-08-01
Series:	Cancer Management and Research
Subjects:	non-small cell lung cancer somatic mutation chinese patients
Online Access:	https://www.dovepress.com/impact-of-somatic-mutations-in-non-small-cell-lung-cancer-a-retrospect-peer-reviewed-article-CMAR

Similar Items

Clinical characteristics and prognostic value of the KRAS G12C mutation in Chinese non-small cell lung cancer patients
by: Si-Yang Liu, et al.
Published: (2020-06-01)

Impact of somatic mutations on prognosis in resected non‐small‐cell lung cancer: The Japan Molecular Epidemiology for lung cancer study
by: Akihiro Tamiya, et al.
Published: (2020-04-01)

Development of somatic mutation signatures for risk stratification and prognosis in lung and colorectal adenocarcinomas
by: Mark Menor, et al.
Published: (2019-01-01)

Identification of candidate genes for lung cancer somatic mutation test kits
by: Yong Chen, et al.
Published: (2013-01-01)

The prevalence and prognostic value of KRAS co‐mutation subtypes in Chinese advanced non‐small cell lung cancer patients
by: Dongjing Cai, et al.
Published: (2020-01-01)

Somatic Mutations and Autoimmunity
by: Maha Alriyami, et al.
Published: (2021-08-01)

Somatic evolutionary timings of driver mutations
by: Karen Gomez, et al.
Published: (2018-01-01)

Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants
by: Paulina Galka-Marciniak, et al.
Published: (2019-06-01)

Targeted exome sequencing identifies mutational landscape in a cohort of 1500 Chinese patients with non-small cell lung carcinoma (NSCLC)
by: Ya-jun Zhou, et al.
Published: (2021-04-01)

LUADpp: an effective prediction model on prognosis of lung adenocarcinomas based on somatic mutational features
by: Jiaxian Yu, et al.
Published: (2019-03-01)

The somatic mutation landscape of the human body
by: Pablo E. García-Nieto, et al.
Published: (2019-12-01)

Deep neural network classification based on somatic mutations potentially predicts clinical benefit of immune checkpoint blockade in lung adenocarcinoma
by: Jie Peng, et al.
Published: (2020-01-01)

The NF1 somatic mutational landscape in sporadic human cancers
by: Charlotte Philpott, et al.
Published: (2017-06-01)

Advances on Driver Mutations of Small Cell Lung Cancer
by: Bing TONG, et al.
Published: (2016-04-01)

Characterization of AKT Somatic Mutations in Chinese Breast Cancer Patients
by: Wen L, et al.
Published: (2021-04-01)

Population-based statistical inference for temporal sequence of somatic mutations in cancer genomes
by: Je-Keun Rhee, et al.
Published: (2018-04-01)

Somatic mutations substantially increase the per‐generation mutation rate in the conifer Picea sitchensis
by: Vincent C. T. Hanlon, et al.
Published: (2019-08-01)

Identification of the Prognostic Significance of Somatic Mutation-Derived LncRNA Signatures of Genomic Instability in Lung Adenocarcinoma
by: Wei Geng, et al.
Published: (2021-03-01)

Germline and somatic mutations of multi-gene panel in Chinese patients with epithelial ovarian cancer: a prospective cohort study
by: Wenhui Li, et al.
Published: (2019-08-01)

Understanding and Improving Identification of Somatic Variants
by: Vijayan, Vinaya
Published: (2016)

The association between BRAF mutation class and clinical features in BRAF-mutant Chinese non-small cell lung cancer patients
by: Quan Lin, et al.
Published: (2019-08-01)

POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma
by: Kazuya Shinmura, et al.
Published: (2019-05-01)

KRAS Mutation in Small Cell Lung Carcinoma and Extrapulmonary Small Cell Cancer
by: Hilmi Kodaz, et al.
Published: (2016-08-01)

Differences in actionable genomic alterations between brain metastases and non‑brain metastases in patients with non‑small cell lung cancer
by: Hou, W., et al.
Published: (2022)

Retrospective efficacy analysis of immune checkpoint inhibitors in patients with EGFR‐mutated non‐small cell lung cancer
by: Tadaaki Yamada, et al.
Published: (2019-04-01)

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer
by: Yan You, et al.
Published: (2020-03-01)

Clinical and genetic spectrum of interstitial lung disease in Chinese children associated with surfactant protein C mutations
by: Da Hong, et al.
Published: (2019-08-01)

Real-World Data on Osimertinib in Chinese Patients with Pretreated, EGFR T790M Mutation Positive, Advanced Non-Small Cell Lung Cancer: A Retrospective Study
by: Peng D, et al.
Published: (2021-02-01)

Maximum Somatic Allele Frequency in Combination With Blood-Based Tumor Mutational Burden to Predict the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer: A Pooled Analysis of the Randomized POPLAR and OAK Studies
by: Yu-tong Chen, et al.
Published: (2019-12-01)

Lung Adenocarcinoma with Pulmonary Miliary Metastases and Complex Somatic Heterozygous EGFR Mutation
by: Alexandre Schaller, et al.
Published: (2014-11-01)

Somatic maintenance impacts the evolution of mutation rate
by: Andrii Rozhok, et al.
Published: (2019-08-01)

Decoding tumor mutation burden and driver mutations in early stage lung adenocarcinoma using CT‐based radiomics signature
by: Xiaoxiao Wang, et al.
Published: (2019-10-01)

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
by: Young Seok Ju, et al.
Published: (2014-10-01)

Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data
by: Alexandre Coudray, et al.
Published: (2018-07-01)

Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer
by: Gao X, et al.
Published: (2019-11-01)

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer
by: Xu Liang, et al.
Published: (2018-08-01)

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events
by: Erik N. Bergstrom, et al.
Published: (2019-08-01)

Somatic mutations in neurodegeneration: An update
by: Christos Proukakis
Published: (2020-10-01)

Non-Small-Cell Lung Carcinoma in Women: A Retrospective Cohort Study in Indonesia
by: Noorwati Sutandyo, et al.
Published: (2019-01-01)

Somatization Symptoms in Lung Cancer Patients and Correlative Analysis between Anxiety, Depression and Somatization Symptoms
by: Xinyao ZHANG, et al.
Published: (2017-06-01)