Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle

Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal...

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Main Authors: Seyed Saeid Khalafvand, Tin-Kan Hung, Eddie Yin-Kwee Ng, Liang Zhong
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2015/701945
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spelling doaj-ea3229eb44034948994d11fb88158dfb2020-11-24T23:19:39ZengHindawi LimitedComputational and Mathematical Methods in Medicine1748-670X1748-67182015-01-01201510.1155/2015/701945701945Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left VentricleSeyed Saeid Khalafvand0Tin-Kan Hung1Eddie Yin-Kwee Ng2Liang Zhong3School of Mechanical and Aerospace Engineering, Nanyang Technological University, 639798, SingaporeDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USASchool of Mechanical and Aerospace Engineering, Nanyang Technological University, 639798, SingaporeNational Heart Research Institute of Singapore, National Heart Centre Singapore, 5 Hospital Drive, 169609, SingaporeBlood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model.http://dx.doi.org/10.1155/2015/701945
collection DOAJ
language English
format Article
sources DOAJ
author Seyed Saeid Khalafvand
Tin-Kan Hung
Eddie Yin-Kwee Ng
Liang Zhong
spellingShingle Seyed Saeid Khalafvand
Tin-Kan Hung
Eddie Yin-Kwee Ng
Liang Zhong
Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
Computational and Mathematical Methods in Medicine
author_facet Seyed Saeid Khalafvand
Tin-Kan Hung
Eddie Yin-Kwee Ng
Liang Zhong
author_sort Seyed Saeid Khalafvand
title Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_short Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_fullStr Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_full_unstemmed Kinematic, Dynamic, and Energy Characteristics of Diastolic Flow in the Left Ventricle
title_sort kinematic, dynamic, and energy characteristics of diastolic flow in the left ventricle
publisher Hindawi Limited
series Computational and Mathematical Methods in Medicine
issn 1748-670X
1748-6718
publishDate 2015-01-01
description Blood flow characteristics in the normal left ventricle are studied by using the magnetic resonance imaging, the Navier-Stokes equations, and the work-energy equation. Vortices produced during the mitral valve opening and closing are modeled in a two-dimensional analysis and correlated with temporal variations of the Reynolds number and pressure drop. Low shear stress and net pressures on the mitral valve are obtained for flow acceleration and deceleration. Bernoulli energy flux delivered to blood from ventricular dilation is practically balanced by the energy influx and the rate change of kinetic energy in the ventricle. The rates of work done by shear and energy dissipation are small. The dynamic and energy characteristics of the 2D results are comparable to those of a 3D model.
url http://dx.doi.org/10.1155/2015/701945
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