Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells

Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells

Glioblastoma multiforme (GBM) has a mean survival of only 15 months. Tumour heterogeneity and blood-brain barrier (BBB) mainly hinder the transport of active agents, leading to late diagnosis, ineffective therapy and inaccurate follow-up. The use of hydrogel nanoparticles, particularly hyaluronic ac...

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Bibliographic Details
Main Authors: Angela Costagliola di Polidoro, Giorgia Zambito, Joost Haeck, Laura Mezzanotte, Martine Lamfers, Paolo Antonio Netti, Enza Torino
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
glioblastoma
theranostics
angiopep-2
BBB
active targeting
irinotecan
Online Access:https://www.mdpi.com/2072-6694/13/3/503

Internet

https://www.mdpi.com/2072-6694/13/3/503

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