Out-of-sequence signal 3 as a mechanism for virus-induced immune suppression of CD8 T cell responses.
Virus infections are known to induce a transient state of immune suppression often associated with an inhibition of T cell proliferation in response to mitogen or cognate-antigen stimulation. Recently, virus-induced immune suppression has been linked to responses to type 1 interferon (IFN), a signal...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-09-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC4177909?pdf=render |