Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment

Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment

Homozygous familial hypercholesterolemia is a rare genetic disease featuring extremely high of low-density lipoprotein blood level, cutaneous and tendon xanthomas and accelerated atherosclerosis with often manifestions in the first 2 decades of life, resulting to premature death due to atheroscleros...

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Bibliographic Details
Main Authors: V. К. Zafiraki, Е. D. Kosmacheva, I. N. Zakharova, V. A. Korneva, A. V. Susekov
Format: Article
Language:Russian
Published: Remedium Group LLC 2018-10-01
Series:Медицинский совет
Subjects:
homozygous familial hypercholesterolemia
atherosclerosis
lipid-lowering therapy
Online Access:https://www.med-sovet.pro/jour/article/view/2728
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spelling doaj-ea149d6de65d4c53b98458063ed88a232021-07-28T13:29:38ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902018-10-0101725326010.21518/2079-701X-2018-17-253-2592674Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatmentV. К. Zafiraki0Е. D. Kosmacheva1I. N. Zakharova2V. A. Korneva3A. V. Susekov4Federal State Budgetary Educational Institution of Higher Education Kuban State Medical University of the Ministry of Healthcare of the Russian FederationScientific Research Institution – S.V. Ochapovsky Regional Clinical Hospital № 1Academy for Postgraduate Continuous Medical educationFederal State Budgetary Educational Institution of Higher Education «Petrozavodsk State University»Central Clinical hospital Academy of Medical Sciences; Academy for Postgraduate Continuous Medical educationHomozygous familial hypercholesterolemia is a rare genetic disease featuring extremely high of low-density lipoprotein blood level, cutaneous and tendon xanthomas and accelerated atherosclerosis with often manifestions in the first 2 decades of life, resulting to premature death due to atherosclerosis-related diseases. Modern combined lipid-lowering therapy is able to increase life duration considerably for these patients.https://www.med-sovet.pro/jour/article/view/2728homozygous familial hypercholesterolemiaatherosclerosislipid-lowering therapy
collection DOAJ
language Russian
format Article
sources DOAJ
author V. К. Zafiraki
Е. D. Kosmacheva
I. N. Zakharova
V. A. Korneva
A. V. Susekov
spellingShingle V. К. Zafiraki
Е. D. Kosmacheva
I. N. Zakharova
V. A. Korneva
A. V. Susekov
Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
Медицинский совет
homozygous familial hypercholesterolemia
atherosclerosis
lipid-lowering therapy
author_facet V. К. Zafiraki
Е. D. Kosmacheva
I. N. Zakharova
V. A. Korneva
A. V. Susekov
author_sort V. К. Zafiraki
title Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
title_short Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
title_full Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
title_fullStr Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
title_full_unstemmed Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
title_sort homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
publisher Remedium Group LLC
series Медицинский совет
issn 2079-701X
2658-5790
publishDate 2018-10-01
description Homozygous familial hypercholesterolemia is a rare genetic disease featuring extremely high of low-density lipoprotein blood level, cutaneous and tendon xanthomas and accelerated atherosclerosis with often manifestions in the first 2 decades of life, resulting to premature death due to atherosclerosis-related diseases. Modern combined lipid-lowering therapy is able to increase life duration considerably for these patients.
topic homozygous familial hypercholesterolemia
atherosclerosis
lipid-lowering therapy
url https://www.med-sovet.pro/jour/article/view/2728
work_keys_str_mv AT vkzafiraki homozygousfamilialhypercholesterolemiamodernaspectsofpathogenesisdiagnosticsandtreatment
AT edkosmacheva homozygousfamilialhypercholesterolemiamodernaspectsofpathogenesisdiagnosticsandtreatment
AT inzakharova homozygousfamilialhypercholesterolemiamodernaspectsofpathogenesisdiagnosticsandtreatment
AT vakorneva homozygousfamilialhypercholesterolemiamodernaspectsofpathogenesisdiagnosticsandtreatment
AT avsusekov homozygousfamilialhypercholesterolemiamodernaspectsofpathogenesisdiagnosticsandtreatment
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