Homozygous familial hypercholesterolemia: modern aspects of pathogenesis, diagnostics and treatment
Homozygous familial hypercholesterolemia is a rare genetic disease featuring extremely high of low-density lipoprotein blood level, cutaneous and tendon xanthomas and accelerated atherosclerosis with often manifestions in the first 2 decades of life, resulting to premature death due to atheroscleros...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Remedium Group LLC
2018-10-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/2728 |
| Summary: | Homozygous familial hypercholesterolemia is a rare genetic disease featuring extremely high of low-density lipoprotein blood level, cutaneous and tendon xanthomas and accelerated atherosclerosis with often manifestions in the first 2 decades of life, resulting to premature death due to atherosclerosis-related diseases. Modern combined lipid-lowering therapy is able to increase life duration considerably for these patients. |
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| ISSN: | 2079-701X 2658-5790 |