RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT

RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT

The article presents the experimental studies results of continuous spectrum pulsed UV light mycobactericidal activity against the laboratory strain of Mycobacterium terrae and clinical strains of Mycobacterium tuberculosis with multiple and extensive drug resistance. A pulsed xenon lamp of a mobile...

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Main Authors: V. I. Litvinov, S. G. Safonova, G. E. Freyman, E. P. Selkova, T. A. Grenkova, M. P. Gusarova
Format: Article
Language:Russian
Published: NEW TERRA Publishing House 2018-05-01
Series:Tuberkulez i Bolezni Lëgkih
Subjects:
mycobacterium terrae
clinical strains of mycobacterium tuberculosis
multiple and extensive drug resistance (mdr and xdr)
continuous spectrum pulsed uv light
inactivation efficiency
Online Access:https://www.tibl-journal.com/jour/article/view/1112
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spelling doaj-ea0cca304d9e4b56ad5bcd033ed27dc32021-07-28T20:57:45ZrusNEW TERRA Publishing HouseTuberkulez i Bolezni Lëgkih2075-12302542-15062018-05-01964394610.21292/2075-1230-2018-96-4-39-461112RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHTV. I. Litvinov0S. G. Safonova1G. E. Freyman2E. P. Selkova3T. A. Grenkova4M. P. Gusarova5State Budgetary Healthcare Institution “Moscow Research Center of Tuberculosis Control of the Moscow Health Department”State Budgetary Healthcare Institution “Moscow Research Center of Tuberculosis Control of the Moscow Health Department”State Budgetary Healthcare Institution “Moscow Research Center of Tuberculosis Control of the Moscow Health Department”G. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology of the Federal Service on Customers' Rights Protection and Human Well-Being SurveillanceG. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology of the Federal Service on Customers' Rights Protection and Human Well-Being SurveillanceG. N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology of the Federal Service on Customers' Rights Protection and Human Well-Being SurveillanceThe article presents the experimental studies results of continuous spectrum pulsed UV light mycobactericidal activity against the laboratory strain of Mycobacterium terrae and clinical strains of Mycobacterium tuberculosis with multiple and extensive drug resistance. A pulsed xenon lamp of a mobile “Alfa-01” unit for air decontamination was used as ultraviolet light source. The experiments showed high activity of pulsed UV light against all studied strains, which does not depend on the distance to the treated surface (up to 4 m). The efficiency of contaminated surfaces disinfection reached 100%. Exposing contaminated objects to pulsed xenon UV lamps’ light leads to multiple molecular genetic changes in DNA macromolecules with complete loss of drug resistance to rifampicin and partial loss of drug resistance to isoniazid.https://www.tibl-journal.com/jour/article/view/1112mycobacterium terraeclinical strains of mycobacterium tuberculosismultiple and extensive drug resistance (mdr and xdr)continuous spectrum pulsed uv lightinactivation efficiency
collection DOAJ
language Russian
format Article
sources DOAJ
author V. I. Litvinov
S. G. Safonova
G. E. Freyman
E. P. Selkova
T. A. Grenkova
M. P. Gusarova
spellingShingle V. I. Litvinov
S. G. Safonova
G. E. Freyman
E. P. Selkova
T. A. Grenkova
M. P. Gusarova
RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
Tuberkulez i Bolezni Lëgkih
mycobacterium terrae
clinical strains of mycobacterium tuberculosis
multiple and extensive drug resistance (mdr and xdr)
continuous spectrum pulsed uv light
inactivation efficiency
author_facet V. I. Litvinov
S. G. Safonova
G. E. Freyman
E. P. Selkova
T. A. Grenkova
M. P. Gusarova
author_sort V. I. Litvinov
title RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
title_short RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
title_full RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
title_fullStr RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
title_full_unstemmed RESEARCH OF MYCOBACTERICIDAL ACTIVITY OF CONTINUOUS SPECTRUM PULSED ULTRAVIOLET LIGHT
title_sort research of mycobactericidal activity of continuous spectrum pulsed ultraviolet light
publisher NEW TERRA Publishing House
series Tuberkulez i Bolezni Lëgkih
issn 2075-1230
2542-1506
publishDate 2018-05-01
description The article presents the experimental studies results of continuous spectrum pulsed UV light mycobactericidal activity against the laboratory strain of Mycobacterium terrae and clinical strains of Mycobacterium tuberculosis with multiple and extensive drug resistance. A pulsed xenon lamp of a mobile “Alfa-01” unit for air decontamination was used as ultraviolet light source. The experiments showed high activity of pulsed UV light against all studied strains, which does not depend on the distance to the treated surface (up to 4 m). The efficiency of contaminated surfaces disinfection reached 100%. Exposing contaminated objects to pulsed xenon UV lamps’ light leads to multiple molecular genetic changes in DNA macromolecules with complete loss of drug resistance to rifampicin and partial loss of drug resistance to isoniazid.
topic mycobacterium terrae
clinical strains of mycobacterium tuberculosis
multiple and extensive drug resistance (mdr and xdr)
continuous spectrum pulsed uv light
inactivation efficiency
url https://www.tibl-journal.com/jour/article/view/1112
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AT gefreyman researchofmycobactericidalactivityofcontinuousspectrumpulsedultravioletlight
AT epselkova researchofmycobactericidalactivityofcontinuousspectrumpulsedultravioletlight
AT tagrenkova researchofmycobactericidalactivityofcontinuousspectrumpulsedultravioletlight
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