Enabling Large‐Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas‐Permeable Surfaces
Abstract Patients suffering from acute or sustained thrombocytopenia require platelet transfusions, which are entirely donor‐based and limited by challenges related to storage and fluctuating supply. Developing cell‐culture technologies will enable ex vivo and donor‐independent platelet production....
Main Authors: | Andres F. Martinez, William M. Miller |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-07-01
|
Series: | Stem Cells Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/sctm.18-0160 |
Similar Items
-
Sub-Cellular Localization of Metalloproteinases in Megakaryocytes
by: Alessandro Malara, et al.
Published: (2018-07-01) -
CD34 and CD79a immunopositivity in megakaryocytes
by: Pavithra Ayyanar, et al.
Published: (2021-03-01) -
Salicylate Inhibits Thrombopoiesis in Rat Megakaryocytes by Changing the Membrane Micro-Architecture
by: Itsuro Kazama, et al.
Published: (2015-04-01) -
Airborne particulate matters induce thrombopoiesis from megakaryocytes through regulating mitochondrial oxidative phosphorylation
by: Xiaoting Jin, et al.
Published: (2021-05-01) -
Compensatory Thrombopoietin Production from the Liver and Bone Marrow Stimulates Thrombopoiesis of Living Rat Megakaryocytes in Chronic Renal Failure
by: Itsuro Kazama, et al.
Published: (2011-10-01)