Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress

Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress

To understand the underlying mechanisms of endoplasmic reticulum (ER) stress caused by human rhinovirus (HRV) 16 and non-structural transmembrane protein 2B, the expressions of ER chaperone glucose-regulated protein 78 (GRP78) and three signal transduction pathways, including protein kinase RNA-like...

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Bibliographic Details
Main Authors: Juan Song, Miaomiao Chi, Xiaonuan Luo, Qinqin Song, Dong Xia, Bingtian Shi, Jun Han
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
HRV16 2B protein
endoplasmic reticulum stress
PERK
ATF6
IRE1
Online Access:https://www.mdpi.com/1999-4915/11/2/133

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