Search for antibacterial activity in a number of new S-derivatives (1,2,4-triazole-3(2H)-yl)methyl)thiopyrimidines

Search for antibacterial activity in a number of new S-derivatives (1,2,4-triazole-3(2H)-yl)methyl)thiopyrimidines

The relevance of the study of 1,2,4-triazole derivatives with pyrimidine fragment is due to the synthesis of potential broad-spectrum antibacterial drugs, low molecular weight inducers of interferon, and antitumor agents, search for molecular descriptors of their structure, important for establishin...

Full description

Bibliographic Details
Main Authors:	Yu. V. Karpenko, O. I. Panasenko
Format:	Article
Language:	English
Published:	Zaporozhye State Medical University 2021-07-01
Series:	Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:	1 2 4-triazole pyrimidines antibacterial activity qsar
Online Access:	http://pharmed.zsmu.edu.ua/article/view/234565/235025

Similar Items

Antibacterial Activity of Fluorobenzoylthiosemicarbazides and Their Cyclic Analogues with 1,2,4-Triazole Scaffold
by: Urszula Kosikowska, et al.
Published: (2021-12-01)

1,2,4-Triazoles as Important Antibacterial Agents
by: Małgorzata Strzelecka, et al.
Published: (2021-03-01)

Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine
by: Ramdas Bhanudas Pandhare, et al.
Published: (2013-02-01)

Synthesis, antibacterial and surface activity of 1,2,4-triazole derivatives
by: R. El-Sayed
Published: (2006-06-01)

The study of the antimicrobial activity of the derivatives of 6-(1,2,4-oxadizol-3-yl)- and 6-(2-aminothiazol-4-yl)thieno[2,3-d]pyrimidin-4-ones by the double dilution method
by: Sergiy V. Vlasov, et al.
Published: (2019-09-01)

In silico study of new bis-3R, 4R′-5-(((1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1,2,4-triazole-3-thione derivatives
by: Ye. O. Karpun, et al.
Published: (2019-12-01)

2-Amino-5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one
by: Sanae Lahmidi, et al.
Published: (2018-11-01)

Synthesis of New 1,2,3-Triazole Derivatives of Uracil and Thymine with Potential Inhibitory Activity against Acidic Corrosion of Steels
by: Mario A. Romero-Romo, et al.
Published: (2013-04-01)

Synthesis, antimicrobial, anticancer evaluation and QSAR studies of N′-substituted benzylidene/2-hydroxynaphthalen-1-ylmethylene/3-phenylallylidene/5-oxopentylidene -4-(2-oxo-2-(4H-1,2,4-triazol-4-yl) methylamino)benzohydrazides
by: Sumit Tahlan, et al.
Published: (2017-05-01)

Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol
by: T. V. Kravchenko, et al.
Published: (2017-04-01)

Ethyl 2-(5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7-yl)pent-4-enoate
by: Sanae Lahmidi, et al.
Published: (2018-09-01)

New S-alkylated 1,2,4-triazoles incorporating diphenyl sulfone moieties with potential antibacterial activity
by: Barbuceanu Stefania F., et al.
Published: (2009-01-01)

New S-alkylated 1,2,4-triazoles incorporating diphenyl sulfone moieties with potential antibacterial activity
by: STEFANIA F. BARBUCEANU, et al.
Published: (2009-09-01)

Biological activity of the derivatives of 1,2,4-triazole
by: T. V. Kravchenko, et al.
Published: (2018-08-01)

Synthesis and antimicrobial activity of s-substituted derivatives of 1,2,4-triazol-3-thiol
by: Yevhen Karpun, et al.
Published: (2021-06-01)

IN SILICO STUDY FOR INVESTIGATING AND PREDICTING THE ACTIVITIES OF 1,2,4-TRIAZOLE DERIVATIES AS POTENT ANTI-TUBERCULAR AGENTS
by: SHOLA ELIJAH ADENIJI, et al.
Published: (2018-07-01)

The search of new biologically active compounds with antibacterial and antifungal activity among 1,2,4-triazole-3-thiol derivatives with the remnants of thiophene
by: V. O. Salionov, et al.
Published: (2017-08-01)

Computational investigation, virtual docking simulation of 1, 2, 4-Triazole analogues and insillico design of new proposed agents against protein target (3IFZ) binding domain
by: Shola Elijah Adeniji, et al.
Published: (2020-08-01)

Actoprotective activity of 2-(4-r-3-(thiophen-2-yl)-4h-1,2,4-triazol-3-ylthio) acetic acid
by: V. O. Salionov, et al.
Published: (2017-03-01)

Research of the antimicrobial and antifungal activity of 7-((3-thio-4-R-4H-1,2,4-triazoles-3-yl)methyl)theophylline S-derivatives
by: A. S. Gotsulya Ye. G. Knysh, et al.
Published: (2015-08-01)

Determination of antimicrobial activity of some 1,2,4-triazole derivatives
by: M. S. M. Alrawashdeh
Published: (2018-04-01)

Synthesis and investigation of the physicochemical properties of 2-(5-((theophylline-7'-yl)methyl)-4-phenyl-4H-1,2,4-triazole-3-ylthio)-acetic acid salts
by: A. S. Gotsulya, et al.
Published: (2014-02-01)

Synthesis and physical-chemical properties of 3-alkylthio-5-(quinoline-2-yl, 2-hydroxyquinoline-4-yl)-4-R-2,4-dihydro-3H-1,2,4-triazoles
by: T. M. Kaplaushenko, et al.
Published: (2016-06-01)

QSAR study by 1,2,4-triazoles using several physicochemical descriptors
by: Vesna Dimova, et al.
Published: (2009-06-01)

Anti-inflammatory activity of 2-(5-((theophylline-7'-yl)methyl)-4-R-4H-1,2,4-triazole-3-ylthio)acetic acid salts
by: A. S. Gotsulya, et al.
Published: (2014-12-01)

Synthesis, antimicrobial, anticancer evaluation and QSAR studies of N '-substituted benzylidene/2-hydroxynaphthalen-1-ylmethylene/3-phenylallylidene/5-oxopentylidene-4-(2-oxo-2-(4H-1,2,4-triazol-4-yl) methylamino)benzohydrazides
by: Kumar, P, et al.
Published: (2017)

Synthesis, physical and chemical properties, antihypoxic activity of some 5-[((5-(adamantane-1-yl)-4-R-4H-1,2,4-triazole-3-yl)thio)methyl]-N-R1-1,3,4-thiadiazole-2-amines and 5-[((5-(adamantane-1-yl)-4-R-4H-1,2,4-triazole-3-yl)thio)methyl]-4-R1-4H-1,2,4-t
by: V. M. Odyntsova, et al.
Published: (2018-03-01)

Actoprotective properties of 7'-((3-thio-4-methyl-4H-1,2,4-triazole-5-yl)methyl)theophylline derivatives
by: A. S. Gotsulya
Published: (2016-06-01)

Antifatigue action of the 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thione alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2018-08-01)

Syntheses, Antibacterial and Antifungal Activities of Substituted-Thiazolo-1,3,4-Thiadiazoles, 1,3,4-Oxadiazoles and 1,2,4-Thiazoles
by: Abbas Shafiee, et al.
Published: (1998-06-01)

Dataset on in-silico investigation on triazole derivatives via molecular modelling approach: A potential glioblastoma inhibitors
by: Abel Kolawole Oyebamiji, et al.
Published: (2021-02-01)

Dataset on the DFT-QSAR, and docking approaches for anticancer activities of 1, 2, 3-triazole-pyrimidine derivatives against human esophageal carcinoma (EC-109)
by: Rhoda Oyeladun Adegoke, et al.
Published: (2020-08-01)

Acute toxicity of 2-(5-(adamantane-1-yl)-4R-1,2,4-triazole-3-ylthio) of the acetic acids and their salts’ derivatives
by: V. M. Odyntsova, et al.
Published: (2015-12-01)

Quantitative structure activity relationships of some N1-aryl/heteroarylaminomethyl/ethyl-1,2,4-triazoles
by: Vesna Dimova, et al.
Published: (2006-06-01)

Analgesic activity of 4-amino-5-methyl-4H-1,2,4-triazol-3-thiones
by: T. V. Kravchenko, et al.
Published: (2018-10-01)

Dataset on theoretical bio-evaluation of 1,2,4-thiadiazole-1,2,4-triazole analogues against epidermal growth factor receptor kinase down regulating human lung cancer
by: Abel Kolawole Oyebamiji, et al.
Published: (2021-08-01)

Discovery of Novel Triazole-Containing Pyrazole Ester Derivatives as Potential Antibacterial Agents
by: Ming-Jie Chu, et al.
Published: (2019-04-01)

The study of morpholinium 2-[5-(pyridin-4yl)-1,2,4-triazol-3-ylthio]acetate effect on prevention of stressful conditions
by: I. V. Bushueva, et al.
Published: (2014-08-01)

Design, Synthesis, and Antimicrobial Activity of Certain New Indole-1,2,4 Triazole Conjugates
by: Reem I. Al-Wabli, et al.
Published: (2021-04-01)

Diuretic activity of 3-(5-bromfuran-2-yl)-4-r-(4h)-1,2,4-triazole-5-thione, their S-derivatives and 2-(5-bromfuran-2-yl)-5-r'-thiazolo[3,2-b][1,2,4]triazole-6(5h)-ones
by: Ye. S. Pruglo, et al.
Published: (2015-12-01)

Cannot write session to /tmp/vufind_sessions/sess_447h637t3qjaf81oj6sdc0qrld