MITF Promotes Cell Growth, Migration and Invasion in Clear Cell Renal Cell Carcinoma by Activating the RhoA/YAP Signal Pathway

MITF Promotes Cell Growth, Migration and Invasion in Clear Cell Renal Cell Carcinoma by Activating the RhoA/YAP Signal Pathway

Microphthalmia-associated transcription factor (MITF) is a basic helix-loop-helix leucine zipper transcription factor involved in the lineage-specific regulation of melanocytes, osteoclasts and mast cells. MITF is also involved in the progression of melanomas and other carcinomas, including the live...

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Bibliographic Details
Main Authors: Nayoung Kim, Solbi Kim, Myung-Won Lee, Heung-Jin Jeon, Hyewon Ryu, Jin-Man Kim, Hyo-Jin Lee
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
renal cell carcinoma
MITF
RhoA
YAP
proliferation
cell cycle
Online Access:https://www.mdpi.com/2072-6694/13/12/2920

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