Reconciling mediating and slaving roles of water in protein conformational dynamics.
Proteins accomplish their physiological functions with remarkably organized dynamic transitions among a hierarchical network of conformational substates. Despite the essential contribution of water molecules in shaping functionally important protein dynamics, their exact role is still controversial....
Main Authors: | Li Zhao, Wenzhao Li, Pu Tian |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3623917?pdf=render |
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