Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

Tetra-O-methyl nordihydroguaiaretic acid (Terameprocol) inhibits the NF-κB-dependent transcription of TNF-α and MCP-1/CCL2 genes by preventing RelA from binding its cognate sites on DNA

<p>Abstract</p> <p>Background</p> <p>Tetra-O-methyl nordihydroguaiaretic acid, also known as terameprocol (TMP), is a naturally occurring phenolic compound found in the resin of the creosote bush. We have shown previously that TMP will suppress production of certain inf...

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Bibliographic Details
Main Authors: Scholle Frank, Wilson Jason R, Sikes Michael L, Oyegunwa Akinbolade O, Laster Scott M
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/7/1/59

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http://www.journal-inflammation.com/content/7/1/59

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