A survey of conformational and energetic changes in G protein signaling

A survey of conformational and energetic changes in G protein signaling

Cell signaling is a fundamental process for all living organisms. G protein-coupled receptors (GPCRs) are a large and diverse group of transmembrane receptors which convert extracellular signals into intracellular responses primarily via coupling to heterotrimeric G proteins. In order to integrate t...

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Bibliographic Details
Main Authors: Alyssa D. Lokits, Julia Koehler Leman, Kristina E. Kitko, Nathan S. Alexander, Heidi E. Hamm, Jens Meiler
Format: Article
Language:English
Published: AIMS Press 2015-11-01
Series:AIMS Biophysics
Subjects:
heterotrimeric G protein
G protein coupled receptor
energetic
ROSETTA
modeling
pairwise interactions
Online Access:http://www.aimspress.com/biophysics/article/498/fulltext.html

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