Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (<it>fut8</it>) expressed in the rat hybridoma cell line YB2/0

Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (<it>fut8</it>) expressed in the rat hybridoma cell line YB2/0

<p>Abstract</p> <p>Background</p> <p>The rat hybridoma cell line YB2/0 appears a good candidate for the large-scale production of low fucose recombinant mAbs due to its lower expression of <it>fut8 </it>gene than other commonly used rodent cell lines. Howeve...

Full description

Bibliographic Details
Main Authors: Harduin-Lepers Anne, Bobowski Marie, Meurice Edwige, Teylaert Béatrice, Gaucher Christine, Fontayne Alexandre, Jorieux Sylvie, Delannoy Philippe
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/1

Internet

http://www.biomedcentral.com/1472-6750/11/1

Similar Items