Exploration of the Key Proteins in the Normal-Adenoma-Carcinoma Sequence of Colorectal Cancer Evolution Using In-Depth Quantitative Proteomics

Purpose. In most cases, the carcinogenesis of colorectal cancer (CRC) follows the normal-adenoma-carcinoma (N-A-C) sequence. In this study, we aimed to identify the key proteins in the N-A-C sequence. Methods. Differentially expressed proteins (DEPs) in normal, adenoma, and carcinoma tissues were id...

Full description

Bibliographic Details
Main Authors: Yin Zhang, Chun-Yuan Li, Wei Ge, Yi Xiao
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2021/5570058