Mitochondrial Fragmentation and Dysfunction in Type IIx/IIb Diaphragm Muscle Fibers in 24-Month Old Fischer 344 Rats
Sarcopenia is characterized by muscle fiber atrophy and weakness, which may be associated with mitochondrial fragmentation and dysfunction. Mitochondrial remodeling and biogenesis in muscle fibers occurs in response to exercise and increased muscle activity. However, the adaptability mitochondria ma...
Main Authors: | Alyssa D. Brown, Leah A. Davis, Matthew J. Fogarty, Gary C. Sieck |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-09-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.727585/full |
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