Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery

Objective: To identify risk factors, diagnosis and prognosis associated with ischemic colitis, focusing mainly on patients undergoing surgery. Materials and methods: This retrospective study included all patients admitted to the Centro Hospitalar de São João – E. P. E., diagnosed with ischemic colit...

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Main Authors: Sara Francisca Ferreira Fernandes, Laura Elisabete Ribeiro Barbosa
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2015-10-01
Series:Journal of Coloproctology
Online Access:http://www.sciencedirect.com/science/article/pii/S223793631500074X
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spelling doaj-e9c49cc5a2394e9fadf81680eb5d4d502021-07-02T04:19:33ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632015-10-01354187192Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgerySara Francisca Ferreira Fernandes0Laura Elisabete Ribeiro Barbosa1Medicine School, Universidade do Porto, Porto, Portugal; Corresponding author.Service of General Surgery, Centro Hospitalar São João, EPE, Porto, PortugalObjective: To identify risk factors, diagnosis and prognosis associated with ischemic colitis, focusing mainly on patients undergoing surgery. Materials and methods: This retrospective study included all patients admitted to the Centro Hospitalar de São João – E. P. E., diagnosed with ischemic colitis during the period from 2012 to 2013. Results: The study included 154 patients; 118 were undergoing medical treatment, with a 12% mortality rate, and 36 were undergoing surgery, with a 61% associated mortality rate. Hypertension was the most common risk factor in both groups. The presence of a large number of cardiovascular risk factors in both groups, such as hypertension and dyslipidemia, was recorded, but we still found no direct relationship with development of ischemic colitis. Comorbidities that affect blood flow, such as the presence of thrombi or aneurysms, do provide a worse prognosis and therefore require a more aggressive treatment. Conclusion: The diagnosis of ischemic colitis is not always immediately established due to a nonspecific presentation. Surgical treatment should be reserved for severe cases with a worse prognosis associated. Resumo: Objetivos: Identificar fatores de risco, diagnóstico e prognóstico associados à colite isquémica, incidindo mais em doentes submetidos à cirurgia. Materiais e métodos: O estudo retrospetivo incluiu todos os doentes admitidos no Centro Hospitalar de São João–E. P. E. com diagnóstico de colite isquémica durante o período de 2012 a 2013. Resultados: O estudo incluiu 154 doentes; desses, 118 foram submetidos a tratamento médico, com uma taxa de mortalidade de 12%, e 36 foram submetidos a tratamento cirúrgico, com uma taxa de mortalidade associada de 61%. Hipertensão arterial foi o fator de risco mais comum em ambos os grupos. Foi registada a presença de grande número de fatores de risco cardiovasculares em ambos os grupos, como hipertensão arterial e dislipidemia, mas ainda não foi encontrada nenhuma relação direta com o desenvolvimento de colite isquémica. Comorbilidades que afetam o fluxo sanguíneo, como a presença de trombos ou aneurismas, fazem prever um pior prognóstico e, por isso, exigem maior agressividade no tratamento. Conclusão: O diagnóstico de colite isquémica nem sempre é imediato, devido a uma apresentação pouco específica. O tratamento cirúrgico deverá ser reservado para casos mais severos, tendo pior prognóstico associado. Keywords: Ischemic colitis, Colitis, Risk factors, Prognosis, Palavras-chave: Colite isquémica, Colite, Fatores de risco, Prognósticohttp://www.sciencedirect.com/science/article/pii/S223793631500074X
collection DOAJ
language English
format Article
sources DOAJ
author Sara Francisca Ferreira Fernandes
Laura Elisabete Ribeiro Barbosa
spellingShingle Sara Francisca Ferreira Fernandes
Laura Elisabete Ribeiro Barbosa
Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
Journal of Coloproctology
author_facet Sara Francisca Ferreira Fernandes
Laura Elisabete Ribeiro Barbosa
author_sort Sara Francisca Ferreira Fernandes
title Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
title_short Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
title_full Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
title_fullStr Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
title_full_unstemmed Ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
title_sort ischemic colitis: risk factors, diagnosis and prognosis in patients undergoing surgery
publisher Thieme Revinter Publicações Ltda.
series Journal of Coloproctology
issn 2237-9363
publishDate 2015-10-01
description Objective: To identify risk factors, diagnosis and prognosis associated with ischemic colitis, focusing mainly on patients undergoing surgery. Materials and methods: This retrospective study included all patients admitted to the Centro Hospitalar de São João – E. P. E., diagnosed with ischemic colitis during the period from 2012 to 2013. Results: The study included 154 patients; 118 were undergoing medical treatment, with a 12% mortality rate, and 36 were undergoing surgery, with a 61% associated mortality rate. Hypertension was the most common risk factor in both groups. The presence of a large number of cardiovascular risk factors in both groups, such as hypertension and dyslipidemia, was recorded, but we still found no direct relationship with development of ischemic colitis. Comorbidities that affect blood flow, such as the presence of thrombi or aneurysms, do provide a worse prognosis and therefore require a more aggressive treatment. Conclusion: The diagnosis of ischemic colitis is not always immediately established due to a nonspecific presentation. Surgical treatment should be reserved for severe cases with a worse prognosis associated. Resumo: Objetivos: Identificar fatores de risco, diagnóstico e prognóstico associados à colite isquémica, incidindo mais em doentes submetidos à cirurgia. Materiais e métodos: O estudo retrospetivo incluiu todos os doentes admitidos no Centro Hospitalar de São João–E. P. E. com diagnóstico de colite isquémica durante o período de 2012 a 2013. Resultados: O estudo incluiu 154 doentes; desses, 118 foram submetidos a tratamento médico, com uma taxa de mortalidade de 12%, e 36 foram submetidos a tratamento cirúrgico, com uma taxa de mortalidade associada de 61%. Hipertensão arterial foi o fator de risco mais comum em ambos os grupos. Foi registada a presença de grande número de fatores de risco cardiovasculares em ambos os grupos, como hipertensão arterial e dislipidemia, mas ainda não foi encontrada nenhuma relação direta com o desenvolvimento de colite isquémica. Comorbilidades que afetam o fluxo sanguíneo, como a presença de trombos ou aneurismas, fazem prever um pior prognóstico e, por isso, exigem maior agressividade no tratamento. Conclusão: O diagnóstico de colite isquémica nem sempre é imediato, devido a uma apresentação pouco específica. O tratamento cirúrgico deverá ser reservado para casos mais severos, tendo pior prognóstico associado. Keywords: Ischemic colitis, Colitis, Risk factors, Prognosis, Palavras-chave: Colite isquémica, Colite, Fatores de risco, Prognóstico
url http://www.sciencedirect.com/science/article/pii/S223793631500074X
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