Chelerythrine chloride from Macleaya cordata induces growth inhibition and apoptosis in human gastric cancer BGC-823 cells

Chelerythrine chloride from Macleaya cordata induces growth inhibition and apoptosis in human gastric cancer BGC-823 cells

This study aimed to investigate the ability of chelerythrine chloride (CHE), the main active ingredient of Macleaya cordata, to induce apoptosis in human gastric cancer BGC-823 cells. The results demonstrate that CHE inhibits cell proliferation in a time- and dose-dependent manner with accompanying...

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Bibliographic Details
Main Authors: Zhengfu Zhang, Ying Guo, Lingwei Zhang, Jianbin Zhang, Xionghui Wei
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Macleaya cordata
Chelerythrine chloride
BGC-823 cells
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383512000305

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