Pioglitazone Attenuates Reoxygenation Injury in Renal Tubular NRK-52E Cells Exposed to High Glucose via Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress

Pioglitazone Attenuates Reoxygenation Injury in Renal Tubular NRK-52E Cells Exposed to High Glucose via Inhibiting Oxidative Stress and Endoplasmic Reticulum Stress

Renal ischemia-reperfusion injury is a major cause of acute kidney injury. In the present study, we investigated the effects of pioglitazone on hypoxia/reoxygenation (H/R) injury in rat renal tubular epithelial cells (RTECs) under normal- (NG) or high-glucose (HG) culture conditions via evaluating o...

Full description

Bibliographic Details
Main Authors: Cong Zou, Zhiyu Zhou, Yunming Tu, Weichao Wang, Tongchang Chen, Honglin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
pioglitazone
hypoxia/reoxygenation injury
high glucose
endoplasmic reticulum stress
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01607/full

Similar Items

Similar Items