Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial

Effects of maternal folic acid supplementation during the second and third trimesters of pregnancy on neurocognitive development in the child: an 11-year follow-up from a randomised controlled trial

Abstract Background Maternal folic acid (FA) supplementation before and in early pregnancy prevents neural tube defects (NTD), but it is uncertain whether continuing FA after the first trimester has benefits on offspring health. We aimed to evaluate the effect of FA supplementation throughout pregna...

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Bibliographic Details
Main Authors: Aoife Caffrey, Helene McNulty, Mark Rollins, Girijesh Prasad, Pramod Gaur, Joel B. Talcott, Caroline Witton, Tony Cassidy, Barry Marshall, James Dornan, Adrian J. Moore, Mary Ward, J. J. Strain, Anne M. Molloy, Marian McLaughlin, Diane J. Lees-Murdock, Colum P. Walsh, Kristina Pentieva
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medicine
Subjects:
Prenatal folic acid
Pregnancy
Randomised controlled trial
Child cognition
Neuronal function
Wechsler Intelligence Scale for Children
Online Access:https://doi.org/10.1186/s12916-021-01914-9

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