Intraocular Injection of ES Cell-Derived Neural Progenitors Improve Visual Function in Retinal Ganglion Cell-Depleted Mouse Models

Intraocular Injection of ES Cell-Derived Neural Progenitors Improve Visual Function in Retinal Ganglion Cell-Depleted Mouse Models

Retinal ganglion cell (RGC) transplantation is a promising strategy to restore visual function resulting from irreversible RGC degeneration occurring in glaucoma or inherited optic neuropathies. We previously demonstrated FGF2 induced differentiation of mouse embryonic stem cells (ESC) to RGC lineag...

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Bibliographic Details
Main Authors: Mundackal S. Divya, Vazhanthodi A. Rasheed, Tiffany Schmidt, Soundararajan Lalitha, Samer Hattar, Jackson James
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
embryonic stem cell derived neural progenitors
retinal ganglion cells
glaucoma
transplantation
functional integration
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00295/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00295/full

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