ZAK negatively regulates RhoGDIβ-induced Rac1-mediated hypertrophic growth and cell migration

<p>Abstract</p> <p>RhoGDIβ, a Rho GDP dissociation inhibitor, induced hypertrophic growth and cell migration in a cultured cardiomyoblast cell line, H9c2. We demonstrated that RhoGDIβ plays a previously undefined role in regulating Rac1 expression through transcription to induce hy...

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Bibliographic Details
Main Authors: Chang I-Chang, Liu Kuan-Yu, Yang Li-Chiu, Huang Chih-Yang, Liao Pao-Hsin, Chou Janet, Chou Ming-Yung, Lin Wei-Wen, Yang Jaw-Ji
Format: Article
Language:English
Published: BMC 2009-06-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/16/1/56