Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes.

Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes.

Dietary restriction (DR), limiting nutrient intake from diet without causing malnutrition, delays the aging process and extends lifespan in multiple organisms. The conserved life-extending effect of DR suggests the involvement of fundamental mechanisms, although these remain a subject of debate. To...

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Bibliographic Details
Main Authors: Daniel Wuttke, Richard Connor, Chintan Vora, Thomas Craig, Yang Li, Shona Wood, Olga Vasieva, Robert Shmookler Reis, Fusheng Tang, João Pedro de Magalhães
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3415404?pdf=render

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