Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes

<p>Abstract</p> <p>Background</p> <p>Immature B lymphocytes and certain B cell lymphomas undergo apoptotic cell death following activation of the B cell antigen receptor (BCR) signal transduction pathway. Several biochemical changes occur in response to BCR engagement,...

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Bibliographic Details
Main Authors: Lee Jamie A, Hammill Adrienne M, Hsueh Robert C, Uhr Jonathan W, Scheuermann Richard H
Format: Article
Language:English
Published: BMC 2002-12-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/3/16