Immunogenicity of a polyvalent HIV-1 candidate vaccine based on fourteen wild type gp120 proteins in golden hamsters

<p>Abstract</p> <p>Background</p> <p>One of the major obstacles in the design of an effective vaccine against HIV-1 is the hypervariability of the HIV-1 envelope glycoprotein. Most HIV-1 vaccine candidates have utilized envelope glycoprotein from a single virus isolate,...

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Bibliographic Details
Main Authors: Ghorbani Masoud, Anderson David E, Azizi Ali, Gee Katrina, Diaz-Mitoma Francisco
Format: Article
Language:English
Published: BMC 2006-10-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/7/25