The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes.

All pathogenesis and death associated with Plasmodium falciparum malaria is due to parasite-infected erythrocytes. Invasion of erythrocytes by P. falciparum merozoites requires specific interactions between host receptors and parasite ligands that are localized in apical organelles called micronemes...

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Bibliographic Details
Main Authors: Amrita Dawn, Shailja Singh, Kunal R More, Faiza Amber Siddiqui, Niseema Pachikara, Ghania Ramdani, Gordon Langsley, Chetan E Chitnis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4270784?pdf=render

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