The effects of pegylated interferon alpha 2b on bile-duct ligation induced liver fibrosis in rats

The effects of pegylated interferon alpha 2b on bile-duct ligation induced liver fibrosis in rats

Objective. To test the effects of peginterferon in an unrecoverable model of bile-duct ligation (BDL) induced liver fibrosis.Material and methods.Thirty-seven Wistar rats were divided into five groups: group 1, BDL + peginterferon (n = 8); group 2, BDL (n = 8); group 3, sham + peginterferon (n = 7);...

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Bibliographic Details
Main Authors: Billur Canbakan, Hakan Akin, Gulgun Tahan, Orhan Tarcin, Fatih Eren, Ozlen Atug, Veysel Tahan, Nese Imeryuz, Ozlem Yapicier, Erol Avsar, Nurdan Tozun
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Annals of Hepatology
Subjects:
Peginterferon
Bile duct ligation
Cirrhosis
Liver fibrosis
Collagen
Transforming growth factor β
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119317715

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http://www.sciencedirect.com/science/article/pii/S1665268119317715

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