(S)-(+)-Ketamine hydrochloride
The crystal structure of the title compound {systematic name: (S)-(+)-N-[1-(2-chlorophenyl)-2-oxocyclohexyl]methanaminium chloride}, C13H17ClNO+·Cl−, was determined at 90 (2) K. The (S)-(+)-ketamine hydrochloride salt is a well known anesthetic compound and is...
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2008-08-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536808021053 |
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doaj-e986f83ad3954a3d89190f45aa44235f2020-11-25T00:14:20ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682008-08-01648o1487o148710.1107/S1600536808021053(S)-(+)-Ketamine hydrochloridePatrick HakeyWayne OuelletteJon ZubietaTimothy KorterThe crystal structure of the title compound {systematic name: (S)-(+)-N-[1-(2-chlorophenyl)-2-oxocyclohexyl]methanaminium chloride}, C13H17ClNO+·Cl−, was determined at 90 (2) K. The (S)-(+)-ketamine hydrochloride salt is a well known anesthetic compound and is dramatically more potent than its R isomer. In the title compound, the cyclohexanone ring adopts a chair conformation with the oxo group in the equatorial orientation. The methylamino and 2-chlorophenyl groups at the 2-position have an equatorial and an axial orientation, respectively. The packing of ions is stabilized by an infinite one-dimensional ...Cl...H—N—H...Cl... hydrogen-bonding network, involving NH2+ groups as donors and chloride anions as acceptors.http://scripts.iucr.org/cgi-bin/paper?S1600536808021053 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Patrick Hakey Wayne Ouellette Jon Zubieta Timothy Korter |
| spellingShingle |
Patrick Hakey Wayne Ouellette Jon Zubieta Timothy Korter (S)-(+)-Ketamine hydrochloride Acta Crystallographica Section E |
| author_facet |
Patrick Hakey Wayne Ouellette Jon Zubieta Timothy Korter |
| author_sort |
Patrick Hakey |
| title |
(S)-(+)-Ketamine hydrochloride |
| title_short |
(S)-(+)-Ketamine hydrochloride |
| title_full |
(S)-(+)-Ketamine hydrochloride |
| title_fullStr |
(S)-(+)-Ketamine hydrochloride |
| title_full_unstemmed |
(S)-(+)-Ketamine hydrochloride |
| title_sort |
(s)-(+)-ketamine hydrochloride |
| publisher |
International Union of Crystallography |
| series |
Acta Crystallographica Section E |
| issn |
1600-5368 |
| publishDate |
2008-08-01 |
| description |
The crystal structure of the title compound {systematic name: (S)-(+)-N-[1-(2-chlorophenyl)-2-oxocyclohexyl]methanaminium chloride}, C13H17ClNO+·Cl−, was determined at 90 (2) K. The (S)-(+)-ketamine hydrochloride salt is a well known anesthetic compound and is dramatically more potent than its R isomer. In the title compound, the cyclohexanone ring adopts a chair conformation with the oxo group in the equatorial orientation. The methylamino and 2-chlorophenyl groups at the 2-position have an equatorial and an axial orientation, respectively. The packing of ions is stabilized by an infinite one-dimensional ...Cl...H—N—H...Cl... hydrogen-bonding network, involving NH2+ groups as donors and chloride anions as acceptors. |
| url |
http://scripts.iucr.org/cgi-bin/paper?S1600536808021053 |
| work_keys_str_mv |
AT patrickhakey sketaminehydrochloride AT wayneouellette sketaminehydrochloride AT jonzubieta sketaminehydrochloride AT timothykorter sketaminehydrochloride |
| _version_ |
1725390998500016128 |