Destabilizing DNA during Rejoining Enhances Fidelity of Repair.
A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-08-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4535887?pdf=render |
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doaj-e986573b85a64b8eb982e544223834fb2021-07-02T01:15:00ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852015-08-01138e100221410.1371/journal.pbio.1002214Destabilizing DNA during Rejoining Enhances Fidelity of Repair.Richard RobinsonA new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.http://europepmc.org/articles/PMC4535887?pdf=render |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Richard Robinson |
| spellingShingle |
Richard Robinson Destabilizing DNA during Rejoining Enhances Fidelity of Repair. PLoS Biology |
| author_facet |
Richard Robinson |
| author_sort |
Richard Robinson |
| title |
Destabilizing DNA during Rejoining Enhances Fidelity of Repair. |
| title_short |
Destabilizing DNA during Rejoining Enhances Fidelity of Repair. |
| title_full |
Destabilizing DNA during Rejoining Enhances Fidelity of Repair. |
| title_fullStr |
Destabilizing DNA during Rejoining Enhances Fidelity of Repair. |
| title_full_unstemmed |
Destabilizing DNA during Rejoining Enhances Fidelity of Repair. |
| title_sort |
destabilizing dna during rejoining enhances fidelity of repair. |
| publisher |
Public Library of Science (PLoS) |
| series |
PLoS Biology |
| issn |
1544-9173 1545-7885 |
| publishDate |
2015-08-01 |
| description |
A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article. |
| url |
http://europepmc.org/articles/PMC4535887?pdf=render |
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