Destabilizing DNA during Rejoining Enhances Fidelity of Repair.
A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article.
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-08-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC4535887?pdf=render |
Summary: | A new study shows that during repair of DNA, the effect of a single-strand annealing protein is to destabilize DNA duplex formation so that annealing only occurs between perfectly matched strands; the protein then clamps the strands together for repair. Read the Research Article. |
---|---|
ISSN: | 1544-9173 1545-7885 |