Modulation of Urate Transport by Drugs

Modulation of Urate Transport by Drugs

Background: Serum urate (SU) levels in primates are extraordinarily high among mammals. Urate is a Janus-faced molecule that acts physiologically as a protective antioxidant but provokes inflammation and gout when it precipitates at high concentrations. Transporters play crucial roles in urate dispo...

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Bibliographic Details
Main Authors: Péter Tátrai, Franciska Erdő, Gabriella Dörnyei, Péter Krajcsi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
urate
drug-transporter interactions
in vitro prediction
hyperuricemia
hypouricemia
Online Access:https://www.mdpi.com/1999-4923/13/6/899

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