Two-Species Active Transport along Cylindrical Biofilaments is Limited by Emergent Topological Hindrance

Active motion of molecules along filamentous structures is a crucial feature of cell biology and is often modeled with the paradigmatic asymmetric simple exclusion process. Motivated by recent experimental studies that have addressed the stepping behavior of kinesins on microtubules, we investigate...

Full description

Bibliographic Details
Main Authors: Patrick Wilke, Emanuel Reithmann, Erwin Frey
Format: Article
Language:English
Published: American Physical Society 2018-09-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.8.031063