Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families

Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families

Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in...

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Bibliographic Details
Main Authors: James A. Seddon, Rob M. Warren, Donald A. Enarson, Nulda Beyers, H. Simon Schaaf
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2012-08-01
Series:Emerging Infectious Diseases
Subjects:
tuberculosis and other mycobacteria
child
antimicrobial resistance
familial transmission
Tuberculosis
drug resistance
Online Access:https://wwwnc.cdc.gov/eid/article/18/8/11-1650_article
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spelling doaj-e9677a7297964d8daa78b16374309da52020-11-25T00:33:25ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592012-08-011881342134510.3201/eid1808.111650Drug-Resistant Tuberculosis Transmission and Resistance Amplification within FamiliesJames A. SeddonRob M. WarrenDonald A. EnarsonNulda BeyersH. Simon SchaafDrug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in 2 children. The findings demonstrate the potential for resistance to be transmitted and amplified within families.https://wwwnc.cdc.gov/eid/article/18/8/11-1650_articletuberculosis and other mycobacteriachildantimicrobial resistancefamilial transmissionTuberculosisdrug resistance
collection DOAJ
language English
format Article
sources DOAJ
author James A. Seddon
Rob M. Warren
Donald A. Enarson
Nulda Beyers
H. Simon Schaaf
spellingShingle James A. Seddon
Rob M. Warren
Donald A. Enarson
Nulda Beyers
H. Simon Schaaf
Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
Emerging Infectious Diseases
tuberculosis and other mycobacteria
child
antimicrobial resistance
familial transmission
Tuberculosis
drug resistance
author_facet James A. Seddon
Rob M. Warren
Donald A. Enarson
Nulda Beyers
H. Simon Schaaf
author_sort James A. Seddon
title Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
title_short Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
title_full Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
title_fullStr Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
title_full_unstemmed Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families
title_sort drug-resistant tuberculosis transmission and resistance amplification within families
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2012-08-01
description Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in 2 children. The findings demonstrate the potential for resistance to be transmitted and amplified within families.
topic tuberculosis and other mycobacteria
child
antimicrobial resistance
familial transmission
Tuberculosis
drug resistance
url https://wwwnc.cdc.gov/eid/article/18/8/11-1650_article
work_keys_str_mv AT jamesaseddon drugresistanttuberculosistransmissionandresistanceamplificationwithinfamilies
AT robmwarren drugresistanttuberculosistransmissionandresistanceamplificationwithinfamilies
AT donaldaenarson drugresistanttuberculosistransmissionandresistanceamplificationwithinfamilies
AT nuldabeyers drugresistanttuberculosistransmissionandresistanceamplificationwithinfamilies
AT hsimonschaaf drugresistanttuberculosistransmissionandresistanceamplificationwithinfamilies
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