Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared...

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Main Authors:	Pavel Pazdera, Walid M. Fathalla
Format:	Article
Language:	English
Published:	MDPI AG 2002-01-01
Series:	Molecules
Subjects:	N-(2-cyanophenyl)benzimidoyl chloride thioamide 3 1-benzo-thiazine 1 5-benzotriazocine quinazoline imidoyl chlorides N-imidoyl thioureas
Online Access:	http://www.mdpi.com/1420-3049/7/1/96/

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spelling	doaj-e963713a85fd40d6b5300e2d4b5852892020-11-25T02:34:46ZengMDPI AGMolecules1420-30492002-01-01719610310.3390/70100096Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with ThioamidesPavel PazderaWalid M. FathallaThe reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.http://www.mdpi.com/1420-3049/7/1/96/N-(2-cyanophenyl)benzimidoyl chloridethioamide31-benzo-thiazine135-benzotriazocinequinazolineimidoyl chloridesN-imidoyl thioureas
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Pavel Pazdera Walid M. Fathalla
spellingShingle	Pavel Pazdera Walid M. Fathalla Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides Molecules N-(2-cyanophenyl)benzimidoyl chloride thioamide 3 1-benzo-thiazine 1 3 5-benzotriazocine quinazoline imidoyl chlorides N-imidoyl thioureas
author_facet	Pavel Pazdera Walid M. Fathalla
author_sort	Pavel Pazdera
title	Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_short	Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_full	Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_fullStr	Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_full_unstemmed	Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides
title_sort	synthesis of heterocyclic skeletons by the reaction of n1-(2-cyanophenyl)-benzimidoyl chloride with thioamides
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2002-01-01
description	The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
topic	N-(2-cyanophenyl)benzimidoyl chloride thioamide 3 1-benzo-thiazine 1 3 5-benzotriazocine quinazoline imidoyl chlorides N-imidoyl thioureas
url	http://www.mdpi.com/1420-3049/7/1/96/
work_keys_str_mv	AT pavelpazdera synthesisofheterocyclicskeletonsbythereactionofn12cyanophenylbenzimidoylchloridewiththioamides AT walidmfathalla synthesisofheterocyclicskeletonsbythereactionofn12cyanophenylbenzimidoylchloridewiththioamides
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Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

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