Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

Synthesis of Heterocyclic Skeletons by the Reaction of N1-(2-Cyanophenyl)-benzimidoyl Chloride with Thioamides

The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared...

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Bibliographic Details
Main Authors: Pavel Pazdera, Walid M. Fathalla
Format: Article
Language:English
Published: MDPI AG 2002-01-01
Series:Molecules
Subjects:
N-(2-cyanophenyl)benzimidoyl chloride
thioamide
3
1-benzo-thiazine
1
5-benzotriazocine
quinazoline
imidoyl chlorides
N-imidoyl thioureas
Online Access:http://www.mdpi.com/1420-3049/7/1/96/
Description
Summary:The reaction of N-(2-cyanophenyl)benzimidoyl chloride with reagents containing a thioamide moiety, i.e. thioacetamide, benzylthiourea, symmetrical dialkyl- and diarylthioureas gave different cyclic products: 3,1-benzothiazine, 1,3,5-benzotriazocine and quinazoline. The reaction pathways of prepared compounds are discussed.
ISSN:1420-3049

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