Upregulation of RND3 Affects Trophoblast Proliferation, Apoptosis, and Migration at the Maternal-Fetal Interface

Upregulation of RND3 Affects Trophoblast Proliferation, Apoptosis, and Migration at the Maternal-Fetal Interface

Trophoblasts as the particular cells of the placenta play an important role in implantation and formation of the maternal-fetal interface. RND3 (also known as RhoE) is a unique member of the Rnd subfamily of small GTP-binding proteins. However, its function in cytotrophoblasts (CTBs) at the maternal...

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Bibliographic Details
Main Authors: Xiao-Ling Ma, Xiao Li, Fu-Ju Tian, Wei-Hong Zeng, Jun Zhang, Hui-Qin Mo, Shi Qin, Li-Qun Sun, Yu-Chen Zhang, Yan Zhang, Yi Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
RND3
FOXD3
recurrent miscarriage
trophoblast
ROCK
ERK1/2
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00153/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00153/full

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