Atypical hemolytic uremic syndrome

Atypical hemolytic uremic syndrome

Abstract Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. Most cases of aHUS are caused by uncontrolled complement activation due to genetic mutations in the alternative path...

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Bibliographic Details
Main Authors: Yoko Yoshida, Hideki Kato, Masaomi Nangaku
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Renal Replacement Therapy
Subjects:
Atypical hemolytic uremic syndrome
Complement
Alternative pathway
Complement factor H
Complement component C3
Eculizumab
Online Access:http://link.springer.com/article/10.1186/s41100-016-0088-1

Internet

http://link.springer.com/article/10.1186/s41100-016-0088-1

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